Description:

Pavlov's 1st Edition, "Groundbreaking Lectures on the Work of the Principal Digestive Glands", in Russian

Ivan Pavlov (1849-1936). Lectures on the Work of the Principal Digestive Glands. Moscow: I.N. Kushnereff, 1897. Text in Russian. Unsigned. Octavo, early three-quarter brown morocco, raised bands, patterned endpapers, uncut. With a photographic portrait of Pavlov laid in. Interior generally fine, with inner paper hinges split at free endpapers. Binding handsome. Housed in a custom clamshell box. Rare and important. 

First edition of Pavlov's groundbreaking work, with far-ranging implications in the fields of both physiology and psychology, substantially responsible for him being awarded the Nobel Prize in physiology in 1904. In 1875, Pavlov earned a degree in natural sciences from the University of St. Petersburg, where he developed an interest in physiology, and he obtained his medical degree at the Medical Military Academy in 1879. After completing his doctorate, Pavlov went to Germany, where he studied in Leipzig with Carl Ludwig and Eimear Kelly in the Heidenhain laboratories in Breslau. He remained there from 1884 to 1886. Heidenhain was studying digestion in dogs, using an exteriorized section of the stomach. However, Pavlov perfected the technique by overcoming the problem of maintaining the external nerve supply. The exteriorized section became known as the Heidenhain or Pavlov pouch.

In his own research on the physiology of digestion, Pavlov brought to the task great skill as a surgeon, as well as a method of long-term experimentation that revolutionized the study of physiology. He was successful in producing gastric fistulas without damaging the nerve supply and was also able to create fistulas in the salivary glands, pancreas, and intestines. More importantly, he was able to restore his experimental animals postoperatively to a nearly normal state, and this enabled him to observe them over long periods. Through various experiments, Pavlov was able to demonstrate that the effects of feeding were transmitted to the gastric glands by nervous channels, so that gastric juice could be made to flow from the gastric glands even when food was prevented from entering the stomach. 

Pavlov summarized his experiments in a series of lectures given in 1896 and published in Russian the following year. A German translation appeared in 1898 and an English one in 1902. For his work on the physiology of digestion Pavlov was awarded the Nobel Prize in 1904. In the interim, he had noted that his "Pavlov's dogs" learned the daily routine of the laboratory and would respond with secretion at the approach of the experimenter himself, or in response to some other remote stimulus. This led him to formulate the concept of "conditioned reflex". 

"The elaboration of these experiments and their extension to children demonstrated how great a proportion of human behavior is explicable as a series of conditioned reflexes. Indeed some psychologists seem nowadays to believe that behavior is all. Pavlov's results are, indeed, clearly complementary to those of Freud, and many regard them as of more fundamental significance. Like Freud's, this was the work of one man and a completely new departure" (PMM 385). "Pavlov made perhaps the greatest contribution to our knowledge of the physiology of digestion" (Garrison & Morton 1022). 

This item comes with a Certificate from John Reznikoff, a premier authenticator for both major 3rd party authentication services, PSA and JSA (James Spence Authentications), as well as numerous auction houses.

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